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[1] “We investigated the sonication-assisted extraction (SAE) conditions of Tremella fuciformis polysaccharides. Single-factor experiments showed that the optimal sonication intensity was 6 W/cm2; the other SAE conditions were further optimized using response surface experimental design. A Box-Behnken experiment exhibited that the optimal SAE conditions were temperature, 85°C; ratio of liquid to solid, 46 mL/g; and sonication time, 2 hours. The maximal polysaccharide yield (8.95 g/100 g) was obtained under the optimal extraction conditions. Polysaccharides extracted by sonication or traditional hot water extraction (TWE) were further separated and purified using DEAE-Sepharose and Sephadex G-100 column chromatography. Polysaccharide fractions (SAE-1, SAE-2, TWE-1, and TWE-2) were obtained; their molecular weights were 9.85 × 104, 6.64 × 104, 4.75 × 105, and 2.81 × 105Da, respectively. The total sugar content of SAE-1 and SAE-2 was lower and the protein and nucleic acid contents were higher than those of TWE-1 and TWE-2. In addition, SAE-1 and SAE-2 showed stronger Fe2+-chelating activities and superoxide radical scavenging activities than TWE-1 and TWE-2. This suggests that polysaccharides extracted by sonication possess high antioxidant activities.”

One of the most renowned constituents of ginkgo is Tremella polysaccharides, which has been demonstrated to exert immunomodulatory effects.

It has been demonstrated that Tremella polysaccharides can facilitate the enhancement of the body's immune function by stimulating the activity of immune cells, including macrophages and T cells. Silver Fungus is a rich source of antioxidant compounds, including polyphenolic substances and vitamin E. These components have been demonstrated to effectively scavenge free radicals within the body and reduce oxidative stress within cells. The overproduction of free radicals is intimately associated with a multitude of chronic ailments and the aging process. Consequently, the ingestion of antioxidant compounds can mitigate cellular damage and retard the aging process.

The role of ginkgo polysaccharides in cardiovascular health is becoming an increasingly prominent area of interest. It has been demonstrated that the dietary fibre and polysaccharides present in ginkgo have the capacity to lower cholesterol and regulate lipids.

Tremella is a rich source of dietary fibre, which has been demonstrated to facilitate intestinal motility, enhance digestive processes and prevent constipation. Dietary fibre has the potential to increase the volume of faeces, shorten the passage time of intestinal contents, and promote the growth of beneficial bacteria, thereby regulating the balance of intestinal flora. The ingestion of silver fungus in moderation can assist individuals with impaired intestinal function or indigestion in the resolution of their digestive issues.

[1]https://www.dl.begellhouse.com/journals/708ae68d64b17c52,2dab30ba797125f4,7569c5f864d4acbb.html

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